Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression
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چکیده
منابع مشابه
Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression.
Cyclooxygenase-2 (COX-2), a key enzyme of prostanoid biosynthesis, plays an important role in both hereditary and spontaneous colon cancer. Individuals with ulcerative colitis are also at high risk for colorectal cancer. To investigate the role of Cox-2 in colitis-associated colon cancer, we subjected Cox-2 luciferase-knock-in mice and Cox-2-knockout mice to a well-known mouse model of colitis-...
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متن کاملCompare the effect of ginger extract and aspirin on COX-2 gene expression in colon cancer cell line HT-29
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2010
ISSN: 0143-3334,1460-2180
DOI: 10.1093/carcin/bgq002